Progestins and Recurrence in Breast Cancer Survivors
نویسندگان
چکیده
منابع مشابه
Progestins and recurrence in breast cancer survivors.
Menopausal hormone therapy use in breast cancer survivors is controversial, and clinical trials of this issue have proven diffi cult. Eight years ago, two separate randomized trials of this question were begun, but accrual diffi culties led to development of a merger with a joint analysis plans. In 2004 the trials were stopped early after an interim combined analysis of the pooled data found an...
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متن کاملProgestins and breast cancer.
The relationship between the use of menopausal hormone therapy (ERT, unopposed estrogen therapy; HRT, combined estrogen and progestin therapy) and the development of breast cancer remains controversial. Mechanistic studies examining progestins in human breast cancer cell lines have demonstrated a biphasic cellular response to progesterone; initial exposure to hormone results in a proliferative ...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2005
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/dji100